Imitrex (summatriptan succinate) is a powerful drug usually prescribed for the treatment of classic migraine headaches or cluster headaches. It is structurally similar to serotonin (a neurotransmitter in the brain) and relieves migraines by causing constriction of the arteries leading to the brain. Imitrex is designed to be taken as needed during acute ongoing attacks, and should be started as soon as the symptoms of a headache begin. It is not prescribed on a fixed dosage schedule and has no benefit in preventing migraines or reducing the number of attacks.

Imitrex generally comes in three different forms: tablets, injections, or a nasal spray. The tablet form is the one most commonly prescribed, but the injections possess a faster onset of action. The tablets come in 25, 50, or 100mg pills and may be taken as needed every 2 hours. However, to avoid the risk of overdose, never exceed the maximum daily dosage of 200mg. Tablets should be swallowed whole with a full glass of water. Although the tablets have the advantage of ease of use, they are thought to be less effective because many of the components are metabolized before they reach the target arteries.

Imitrex is a drug with many potential, and sometimes serious, side effects. The most common of these may include a burning sensation, numbness and tingling, a feeling of pressure or tightness, dizziness and drowsiness, sweating, palpitations, shortness of breath, and flushing. Other less common side effects are thirst, agitation, severe chest pain, seizures, sudden weakness, hearing loss, muscle cramps, vision changes and extreme swings in blood pressure.

All users of Imitrex should also be aware of the potential manifestations of an allergic reaction, such as difficulty breathing or swelling of the face and throat. If any of these occur, seek medical attention immediately. Overdose is another possibility if there are any signs of paralysis, tremor, convulsions, lack of coordination, excessive salivation, flushed or bluish extremities, and abnormal breathing patterns.

Imitrex can be a very dangerous drug if taken by someone with heart disease, high blood pressure, poor circulation, high cholestrol, diabetes, or previous history of strokes. The physician should be notified of any other serious health problems and also of any medications being taken.

Imitrex will interact with many over-the-counter drugs and several commonly prescribed antidepressants. It is not recommended for anyone under the age of 18 or over the age of 65. Women who are pregnant or nursing should not take this medication because of the danger of harming the child.

Imitrex is only used for common migraines and not for the rarer hemiplegic or basilar migraines. It is available only by prescription and should be taken exactly as ordered. Dosage rates are individualized for each patient and will vary with body weight and health. Cost per 50mg tablet is about $7.50 in the US. Imitrex is stored at room temperature and should not be exposed to moisture, heat, or light.

Although Imitrex is usually a very effective form a relief from migraine headaches, it has its drawbacks. Obviously this drug is not for everyone, but the majority of people who suffer from migraine headaches can benefit from it. Best of all, most Imitrex users report a favorable experience.

Disclaimer: This information presented should not be interpreted as or substituted for medical advice. If you or someone you know suffers from migraine headaches, consult a qualified professional for the most suitable treatment options available.